|
KMID : 0383820140770060258
|
|
Tuberculosis and Respiratory Diseases
2014 Volume.77 No. 6 p.258 ~ p.261
|
|
|
Bilateral Ovarian Metastases from ALK Rearranged Non-Small Cell Lung Cancer
|
|
Lee Kyung-Ann
Lee Jong-Sik
Min Jae-Ki
Kim Hee-Joung
Kim Wan-Seop
Lee Kye-Young
|
|
|
Abstract
|
|
|
|
Anaplastic lymphoma kinase (ALK) rearrangement, is a kind of driver mutation, accounts for 3%?5% of non-small cell lung cancer (NSCLC). NSCLC patients harboring ALK fusion genes have distinct clinical features and good response to ALK inhibitors. Metastasis from lung cancer to the ovary has rarely been known. We report a case of a 54-year-old woman with bilateral ovarian metastases from ALK rearranged NSCLC. She underwent bilateral salpingo-oophorectomy for ovary masses, which were progressed after cytotoxic chemotherapy although primary lung mass was decreased. Histopathological examination of the ovary tumor showed characteristic adenocarcinoma patterns of the lung and ALK rearrangement.
|
|
|
KEYWORD
|
|
|
Anaplastic Lymphoma Kinase, Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Ovary
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|